“Controlled-release (CR) drug-delivery systems continue to play an important role in the treatment of diseases” – Slew, Pharmaceutical Technology. 2014: 38
The Gettysburg address states that government should be “by the people, for the people.” Medication should also be created for the people. The best medicine is that developed for the specific needs of the patient. Controlled-release drugs help patients by reducing drug burst, reducing interruptions to daily life and improving medication adherence.
Controlled-release medications reduce drug burst. Instead of the API releasing all at once, it releases at a controlled rate. Controlled-release pain relievers can spare patients unnecessary suffering. Controlling the burst in narrow therapeutic index drugs can be lifesaving. “Controlled release (CR) systems for certain medicines including opioids, NSAIDs and antibiotics have demonstrably enhanced treatment efficacy in the post-surgical setting,” according to a 2016 article in Drug Delivery and Translational Research.
Controlled-release drugs can reduce interruptions to patients’ daily lives. A patient who requires conventionally released medication every four to six hours must arrange his or her schedule, including sleep schedule, around taking the medication or risk incompliance and adverse effects or health consequences. Controlled-release drugs allow patients more freedom and convenience in their day-to-day lives.
Controlled-release medications can improve medication adherence. Controlled-release drugs don’t need to be taken as frequently as conventionally released drugs do. The more medications patients have to take and the more frequently they have to take them, the more likely patients are to be noncompliant. A simpler regimen means patients are less likely to forget to take their medications.
Controlled-release drugs help patients by reducing drug burst, reducing interruptions to daily life and improving medication adherence. Orbis Biosciences® recognizes the benefits of controlled-release medications. Our Precision Particle FabricationTM technology is well-suited to the development of controlled-release oral and injectable drugs. We are dedicated to the idea that drugs should be developed to help patients, our people.